Microbiologist Scientist

Location: South San Francisco, CA

Department: R&D

Type: Full Time

Min. Experience: Experienced

Microbiologist Scientist


Second Genome is seeking a motivated researcher ready to join a fast-paced work environment, with experience in a wide range of analytical and experimental techniques, to investigate microbial community dynamics in the context of the human microbiome.  The candidate shall be prepared to plan and execute initiatives to understand the mechanisms of beneficial microbes for advancing microbiome research in human health and disease. The Scientist shall be responsible for discovering and developing novel probiotic bacteria, developing assays to understand the mechanisms of their beneficial effects, isolating novel microbes from clinical samples, and managing the maintenance and culturing of a diverse bacterial culture collection.

Key Attributes and Skills:

  • A PhD degree in Microbiology, Microbial Ecology, Bacteriology, or a related field; 2-3 years (or more) post-graduate and industry experience preferred
  • Expertise in microbial physiology/metabolism, with preferred experience in host-microbiome interactions
  • Experience with aerobic and anaerobic bacterial culturing, with preferred experience with difficult-to-culture organisms
  • Experience in a range of molecular biology techniques (e.g. DNA and RNA work; RT-PCR; qPCR; cloning)
  • Experience with discovering novel gene function through gene-knockout and other mutagenesis techniques
  • Experience with complex microbial community analysis and interpretation, particularly with 16S rRNA gene, metagenomic, and metatranscriptomic datasets
  • Custom assay development experience including concept design, optimization, and validation
  • Experience processing complex biospecimen samples, such as gastrointestinal tissue and stool
  • Capacity to work independently in a startup environment, embracing cross-organizational collaboration with scientists of varied background, data analysts, project managers, and management
  • Excellent interpersonal skills with the ability to effectively communicate
  • Methodical with good attention to detail and exceptional documentation skills
  • A strong publication record that exemplifies the candidate’s ability to succeed in this position
  • A passion to move the field of microbiome science forward

Other highly desirable skills/experience:

  • Experience with basic genomic analysis software and bioinformatics tools
  • Experience with next-generation sequencing (NGS), including operation of instrumentation (Illumina) as well as library preparation for a variety of applications (amplicon sequencing, shotgun sequencing, RNA-seq, etc)



Forward this Position
Recipient email address (one)
Your name
Your email address
Enter a message (optional)
Apply for this Position
* Required fields
First name*
Last name*
Email address*
Phone number*

Attach resume as .pdf, .doc, or .docx (limit 2MB) or paste resume

Paste your resume here or attach resume file

Cover Letter*
In 150 characters or fewer, tell us what makes you unique. Try to be creative and say something that will catch our eye!*
Human Check*